Dr. Kelly’s Curriculum Vitae
JEREMIAH FRANCIS KELLY, M.D.
April 1, 2013
4432 Avenida Del Sol NE
Albuquerque NM, 87110
Boston College, Chestnut Hill, MA. B.A., Magna Cum Laude.
Loyola University, Stritch School of Medicine, Maywood, IL, M.D., June 12, l976.
GRADUATE MEDICAL EDUCATION
Endocrine Research Assistant/March of Dimes student fellowship, Veterans Administration Hospital, Hines Il, and Loyola University Stritch School of Medicine, Maywood, Il. (Preceptor: Ann M. Lawrence, M.D., Ph.D.)
Categorical Internal Medicine Internship and Residency, St. Mary’s Hospital and Medical Center, San Francisco, CA.
Research Fellowship, Clinical Pharmacology, University of California, San Francisco, CA (Preceptor: Roger L. Williams, M.D, UCSF Drug Studies Unit).
Administration on Aging Geriatric Medicine Fellowship, University of California, San Francisco/Mount Zion Hospital and Medical Center, San Francisco, CA.
ADDITIONAL RESEARCH TRAINING
Boehringer Ingelheim Centennial Fellowship (a two year fellowship awarded for research training while full- time faculty member (Assistant Professor of Medicine, Geriatrics) at Boston University Medical Center, Boston, MA.
- Year 1: protected time devoted to coursework (statistics and clinical pharmacokinetics) at Boston University and Tufts University Medical Schools and to neuropharmacology research in laboratory of David J. Greenblatt, Chief, Division of Clinical Pharmacology, Tufts University Medical Center, Boston, MA.
- Year 2: Â full-time clinical neuropharmacology research training and part-time course work (neurochemistry and pharmacokinetics courses) at The Laboratory of Neuroscience, National Institute on Aging (NIA), Intramural Research Program (IRP), Bethesda, MD (Preceptors: Tim Soncrant, MD and Stanley Rappoport MD).
National Research Council Senior Associate (awarded 1990; funded 4/91.) Basic Research Fellowship. (Research was focused on investigating role of oxidative stress as pathogenic mechanism in Alzheimer’s disease, age-related alterations in CNS G protein signaling pathways and age-related changes in composition and function of neuronal lipid rafts.) Laboratory of Cellular and Molecular Biology, Gerontology, IRP, NIA, NIH, Baltimore, MD. Preceptors: George Roth PhD and James Joseph PhD.
NIA Senior Staff Fellow, Laboratory of Cellular and Molecular Biology, IRP, NIA, NIH,(Preceptor: George Roth PhD).
Guest Researcher, Laboratory of Cellular and Molecular Biology, Gerontology Research Center, IRP, NIA, NIH, Baltimore MD 10/97-2/98. (Preceptor: George Roth PhD).
Internal Medicine, American Board of Internal Medicine (ABIM), September 9, 1980. Certificate 79236.
Certificate of Added Qualifications in Geriatric Medicine, ABIM, December 1988; recertification December 1998 and 2009. Certificate # 79236).
Clinical Pharmacology (American Board of Clinical Pharmacology), September 17, 1993. Certificate # 93127.
California G37879 (ceased renewing license in early 2000s.)
Illinois 036-097447 (expiration 7/31/2014)
New Mexico MD 2011-0248 (expiration 7/1/2014)
HONORS and AWARDS
Order of the Cross and Crown, Senior Honor Society, Boston College
March of Dimes, Summer Science Research Training Stipend
Distinguished Graduate, the Pulse Program, Boston College
Boehringer Ingelheim Centennial Fellowship in Clinical Pharmacology
National Research Council Senior Associateship
Smart Family Foundation Scholar, Buehler Center on Aging, Northwestern University
Fellow, Buehler Center on Aging, McGaw Medical Center, Northwestern University
Fellow, Northwestern Alzheimer’s Disease Center, Northwestern University Medical School
Assistant Clinical Professor, Medicine, University of California, San Francisco, CA (teaching appointment).
Assistant Clinical Professor, Pharmacy, University of California, San Francisco, CA (teaching appointment).
Assistant Clinical Professor, Family and Community Medicine, University of California, San Francisco, CA(teaching appointment).
Clinical Assistant Professor, Division of Family and Community Medicine, Stanford University, Palo Alto, CA (teaching appointment for providing geriatrics lectures).
Assistant Professor of Medicine (Geriatrics), Evans Memorial Department of Clinical Research and Assistant Professor of Socio-Medical Sciences and Community Medicine, Boston University Medical Center, Boston, MA. (full-time faculty appointment)
Assistant Professor of Medicine, Division of Geriatrics and Clinical Pharmacology, Department of Medicine, Northwestern University Medical School, Chicago, IL (full-time faculty appointment)
Research Preceptor and Faculty Member, Integrated Graduate Program in the Life Sciences (IGP), Northwestern University Medical School, Chicago, IL. (Yearly summer science research training program for minority students)
Physician-Researcher, Rush Alzheimerâ€™s Disease Center, Rush University Medical Center, Chicago, IL.
Associate Professor of Medicine, Rush University Medical School, Chicago, IL.
Full-time faculty member and Attending Physician, Senior Health Clinic, University of New Mexico School of Medicine, Division of Geriatrics, Department of Internal Medicine, Albuquerque, NM. Academic appointment at UNM was as Assistant Professor of Medicine, pending completion of minidosier for review of credentials for requested appointment as Professor of Medicine, Clinician Educator Track.
HOSPITAL STAFF APPOINTMENTS
Attending Physician, St. Mary’s Hospital and Medical Center, San Francisco, CA.
Attending Physician, University Hospital, Boston, MA.
Attending Physician, Jewish Memorial Hospital, Boston, MA.
Research Physician, Clinical Center, National Institutes of Health, Bethesda, MD.
Associate Medical Staff, Northwestern Memorial Hospital, Chicago, IL.
Consulting Medical Staff, Rehabilitation Institute of Chicago, Chicago, IL.
Director, Geriatrics Clinic, VA Chicago (Lakeside Division), Chicago, IL.
Associate Attending Physician, Rush University Medical Center, Chicago, IL.
Associate Attending Physician, UNM Health Sciences Center, Albuquerque, NM
Geriatrics Consultant and Medical Director, Geriatrics Programs, St. Mary’s Hospital and Medical Center, San Francisco, CA.
Medical Director, Mercy Retirement and Care Center Skilled Nursing Facility, Oakland, CA.
Director (Founding), Geriatric Evaluation Center, The Evans Medical Group, Boston University Medical Center, Boston MA.
Assistant Chief for Education and Co-Director Geriatric Fellowship Program, Geriatrics Section, Boston University Medical Center, Boston, MA.
Medical Director, Whitestone Nursing Home, Chicago, IL.
Director, Geriatrics Clinic, Lakeside Division, VA Chicago Health Care System, Chicago, IL.
Provided scientific direction of and (direct report) administrative supervision of lab manager and 4-5 laboratory technicians who performed biochemistry, cell biology and molecular biology activities and processed and maintained ante-mortem biological samples stored in the human sample repository of the Rush Alzheimer’s Disease Center Laboratory (including frozen serum/plasma, native and EBV-transformed frozen lymphocytes and genomic DNA) of subjects enrolled in the Rush Religious Orders Study and the Rush Memory and Aging Project.
Co-Facillitator, (bimonthly) Dementia Care Clinic, Project ECHO, University of New Mexico, Department of Internal Medicine. The Dementia Care TeleECHO Clinic is designed to assist New Mexico primary care clinicians who lack access to dementia specialists. An interprofessional team of dementia consultants supports and educates primary care clinicians in the provision of multifaceted dementia care. Didactic presentations and case presentations stimulate discussion and create an environment of group learning. Recommendations to presenting clinicians incorporate the most appropriate screening tools, best practice protocols and evidence-based resources, thus educating providers while enabling them to provide the best care possible for their dementia patients.
SUMMARY OF TEACHING EXPERIENCE
University of New Mexico, Geriatrics Section, Department of Internal Medicine
Lecture for Family Practice Residents: “Dementia, An Overview: Diagnosis and Management.”
Thursday School Lecture for Internal Medicine Residents: “Dementia, An Overview: Diagnosis and Management.”
Lecture/Discussion, Senior Health Clinic diabetes patient group (and nursing staff coordinators) attending weekly support group, Information about dementia risk factors and management.
Lecture, Project ECHO Dementia Care Clinic, “Alzheimer’s Dementia Diagnosis”
Lecture and Case Discussion, Geriatric Interest Rounds, “Dementia in the Elderly: Diagnosis.”
Lecture, Project ECHO Dementia Care Clinic, “Future Directions in Dementia Treatment Research”
Faculty Judge, Poster Session, School of Medicine Student Research Day.
Lecture/Discussion,”If it isn’t AD, What is it ?” First Annual Alzheimer’s Disease Professional Conference. Dignity and Diagnosis in Dementia Care. Sponsored by The New Mexico Chapter of the Alzheimer’s Association and Christus St. Vincent Hospital, Santa Fe. NM.
Lecture, Geriatric Interest Rounds: “Diagnosis of MCI and Dementia”
Lecture, Geriatric Interest Rounds, “Future Directions in Dementia Treatment Research”
06/28/2012 Medical Grand Rounds (representing Project ECHO Dementia Care Clinic), Diagnosis and Management of Dementia in the Elderlyâ€ Rehoboth McKinley Hospital, Gallup, New Mexico
Lecture, Project ECHO Dementia Care Clinic, “Diagnosis of Alzheimer’s Disease”
Lecture, Project ECHO Dementia Care Clinic, “Future Directions in Dementia Treatment Research”
Rush University Alzheimer’s Disease Center
Outpatient clinic teaching attending for residents in neurology, family practice and internal medicine rotating through Rush Alzheimer’s Disease Center Memory Clinic.
Research Preceptor for several students doing summer research internship at Rush Alzheimer’s Disease Laboratory (see list of student mentees below).
Northwestern University Medical School:
Teaching Attending, Internal Medicine Service, Lakeside Division, VA Chicago Health Care System.
Preceptor, Second Year Medical Students’ Physical Diagnosis Course.
Boston University Medical Center:
Outpatient Teaching Attending, Boston University Home Medical Service. I saw homebound patients twice a week with a group that usually consisted of 1-2 fourth year medical students, a second or third year internal medicine resident and sometimes a social worker. We usually visited 4-5 patients each afternoon session. All of the patients were elderly and many also suffered from poverty, inadequate housing, poor nutrition, neighborhood crime, family conflicts, drug and alcohol abuse, and lack of knowledge about in-home and community services that were available. In a single afternoon we would typically visit 3-4 very different Boston neighborhoods, including South Boston, The South End, Roxbury, Jamaica Plain and Dorchester.
Teaching Attending, Inpatient Evans Medical Service (2 months a year).
Instructor, Second Year Medical Students’, Physical Diagnosis Course.
Teaching Attending, “Student Morning Report”, Third year, Medical Student Clerkship
Lecturer, Fourth Year Medical Student Lecture Series, Home Medical Service). I gave a monthly lecture to students rotating on The Home Medical Service. The talk usually focused on adverse drug reactions and interactions in the elderly.
Co-Director and Co-Principle Investigator (for three years): The Boston University/American Geriatrics Society Summer Institute on Aging: 1988 (6/20-6/25), 1989 (6/18-6/24) and 1990 (8/5-8/11). The goal of the Summer Institute is to stimulate interest in careers in academic geriatric medicine and aging-related research. This program was established in 1986 and has continued to be offered every year. The primary purpose is to train selected third and fourth year medical students in the principles of clinical geriatrics and geriatrics research. Up to 20 students are selected each year and given opportunities to learn about geriatrics and interact with a group of nationally recognized faculty mentors. Dr. Patricia Barry and I co-directed the program between 1988-1990. I had primary responsibility for running all aspects of the program in 1989 and 1990 after Dr. Barry moved to the University of Florida.
University of California, San Francisco School of Medicine:
Lecturer, Geriatric Medicine Course, Department of Medicine.Â During and after my Geriatrics Fellowship I presented a yearly lecture to students enrolled in the medical school geriatric medicine course. The talk usually focused on Clinical Pharmacology and the Elderly.
Lecturer, Fourth year Medical Student Seminar Series in Geriatrics, Department of Medicine, San Francisco General Hospital. During and after my Geriatrics Fellowship at UCSF I was responsible for presenting a 2 hour seminar in Geriatrics given each month during each rotation of a medical student outpatient medicine elective (for four years). The focus of each monthly talk was on General Principles of Geriatrics.
Housestaff Preceptor, Department of Internal Medicine, St. Mary’s Hospital and Medical Center (St. Mary’s is a UCSF-affiliated teaching program),
- Inpatient Teaching Service and Outpatient Clinic-for one month each year over 3 years.
- Outpatient Clinic Preceptor, Sr. Mary Phillipa Clinic, weekly from 3 years.
Preceptor, Fourth Year Medical Student Outpatient Clinic Rotation, UCSF General Medicine Clinic
Stanford University School of Medicine:
Lecturer, “Multifunctional Evaluation of Elders”, Geriatric Education for Physician Assistant Faculty, Division of Family and Community Medicine. Yearly didactic session for two years.
Lecturer, “Geriatric Functional Evaluation”, Interdepartmental Elective Course: Issues in Geriatric Medicine.
MEDICAL SCHOOL COMMITTEE SERVICE (Contributions to Development of Early UCSF Geriatrics Education Programs)
1984 – 86
Member, Geriatrics in Family Medicine Teaching Group, Division of Family and Community Medicine, University of California San Francisco, School of Medicine, San Francisco, CA. I was invited to participate in this committee by the Chief of Family Practice at UCSF, Dr. Joseph Barbaccia.Â The members were asked to make recommendations regarding the design of a new curriculum in Geriatric Medicine for the FP program.
Chair, Workshop Planning Committee, “Functional Assessment for the Practicing Family Physician,” University of California San Francisco, School of Medicine, San Francisco, CA.
Member, Intern Selection Committee, Department of Medicine, The University Hospital, Boston, MA.
Member, Medical Student Research Committee, Northwestern University Medical School, Chicago, IL.
Faculty Mentor, Summer Research Opportunity Program (SROP) for Underrepresented Minority Undergraduate Students, Northwestern University Graduate School, Chicago, IL.
Member, Tissue Committee, Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, IL.
Member (ad hoc), Executive Committee, Alzheimer’s Disease Core Center, Rush University Medical Center, Chicago, IL.
NIA Gerontology Research Center, Baltimore, MD:
- High School student;
Gerald Lopez (I advised him about and was the preceptor for his project for a national science fair competition while I was a research fellow at the Gerontology Research Center (GRC), NIA, IRP, NIA, NIH). Gerald went on to receive his PhD in electrical engineering. He cited me as a one of his mentors in the opening of his PhD thesis and has stayed in touch over the years.
- Postgraduate Summer Research Fellows
Mohan Rengen, research mentor for postgrad fellowship at Gerontology Research Center, NIA, NIH, Baltimore. Mohan worked with me for one year. He is currently an internist/gastroenterologist in private practice.
Steven Cunningham, worked with me at GRC for two years. He graduated from George Washington University School of Medicine, did his residency in general surgery at the University of Maryland in Baltimore, Maryland, and fellowships in oncology research and in surgery of the liver and pancreas at Johns Hopkins University. He is currently Co-Director of Pancreatic and Hepatobiliary Surgery at Saint Agnes Hospital in Baltimore, MD.
- Research Postdoctoral Fellows:
Regis Perichon PhD, worked with me at GRC for one year (presently Manager, Proteomics Research, Ortho Clinical Diagnostics).
Northwestern University Medical School
Undergraduate and Medical School Students:
Gina Armstrong MD, an undergraduate at Xavier University, came to my lab via the Summer Research Opportunity Program for Minority Undergraduates, (SROP). She is currently a resident in rehabilitation medicine at Mount Sinai Hospital in New York, NY.
Carly Skamra MD, a Beuhler Center on Aging summer research student at Northwestern Medical School.Â Carly is presently a rheumatology fellow at Northwestern Memorial Hospital, Chicago, IL)
Avni Shah MD, an undergraduate student at Texas A&M University who requested a research internship in my lab at Northwestern Medical School and stayed for more almost six months. She is presently a resident in pediatric endocrinology at Children’s Hospital, Los Angeles, CA.
Rush Alzheimer’s Disease Center
Steven Kim, when an undergraduate student at Princeton U, spent two summer internships with me. He has applied to medical school and plans a career as a physician investigator.
Zoe Arvanitakis MD, MS Associate Professor, Neurological Sciences: served asassociate mentor (with David Bennett MD) for NIH K23 AG 023675 (Zoe Arvanitakis) “Oxidative Stress, Aging, and Alzheimer’s Disease”, (1/15/05-12/31/09).
PROFESSIONAL AND SCIENTIFIC ACTIVITY
American Geriatrics Society, (elected a Fellow in 1994)
American College of Physicians (elected a Fellow in 1995)
Society for Neuroscience
American Society for Pharmacology and Experimental Therapeutics (ASPET)
American Medical Directors Association (AMDA). Attended one week Core Curriculum in Medical Direction in Long Term Care Nov 3-9, 2012 in Las Vegas, NV. Plan to apply to be Certified Medical Director (CMD) during 2013.
American College of Physician Executives (will soon complete ACPE prerequisite courses to enroll in MS-HQSM (Masters in Health Quality and Safety Management) masters degree program at Jefferson School of Population Health, Thomas Jefferson University in Fall of 2013.
American Society on Aging
Ongoing Editorial Service Provided
Journal of Neurochemistry, Reviewer
Neurobiology of Aging, Reviewer
Journal of Neuroscience Research, Reviewer
Neuroscience Letters, Reviewer
Journal of Neuroinflammation, Reviewer
Journal of Neuroepidemiology, Reviewer
Scientific Review Committees
Initial Review Board, The Alzheimer’s Association
Alzheimer’s Disease Research Fund Peer Review Panel, State of Illinois
PROFESSIONAL PUBLIC SERVICE
Member, Respite Care Steering Committee, Catholic Social Services, San Francisco, CA.
Co-Chair Health Care Section, Program Planning Committee, 1987 Annual Meeting, American Society on Aging
Member, Stroke Committee, American Heart Association, San Francisco Chapter
Member, Multidisciplinary Team, Consortium for Elder Abuse Prevention, San Francisco
Panel Member, NIH Consensus Development Conference on Differential Diagnosis of Dementing Diseases
Co-Chair, American Geriatrics Society Ad Hoc Committee on Implementation of Fellowship Guidelines
Site Visitor, Residency Review Committee for Internal Medicine, Geriatric Fellowship Program Accreditation
Pre-reviewer, Subspecialty Panel for Internal Medicine – Geriatrics, Residency Review Committee for Internal Medicine
Member, Education Committee, American Geriatrics Society
Representative (alternate) to the Association of American Medical Colleges, Council of Academic Societies, American Geriatrics Society
Member, Task Force on Expanding Medical Student Education in Geriatrics
Member, Standing Panel for Accreditation Appeals, Internal Medicine-Geriatrics, Accreditation Council for Graduate Medical Education
Member, Research Committee, American Geriatrics Society
Co-Chair, Neurological and Behavioral Studies Abstract Review Section, American Geriatrics Society Annual Meeting
Chair, Foundation for Health in Aging Sub-committee, Research Committee, American Geriatrics Society
Member, Board of Appeals, Panel for Internal Medicine Subspecialty of Geriatrics, Accreditation Council for Graduate Medical Education.
Clinical Advisor, New Mexico Chapter of the Alzheimer’s Association (Voluntary).
FUNDED RESEARCH GRANTS/CONTRACTS
Principal Investigator, Northwestern Memorial Hospital Intramural Research Grants Program “Effect of Aging and Dietary Lipid Modulation on the Distribution of Muscarinic Receptors and G Proteins in Cortical and Hippocampal Caveolae of F344 Rats.”
Principal Investigator, Northwestern Memorial Hospital Foundation, “Effects of Clinical Stage and ApoE4 Genotype on G Protein Targeting to Caveolae in Alzheimer’s Disease” 12/01/01-6/30/02.
Principal Investigator, NIH, 1RO3 AG19493-01, “Cholesterol Effects on Caveolin-G Protein Interactions”, 4/01/01-3/31/03.
Principal Investigator, Rush Alzheimer’s Disease Core Center Pilot Project Grant, “Relation of Oxidative Stress and Inflammation to Cognitive Function in Older Persons with and Without AD”, 9/20/02-5/31/03.
Co-Investigator, NIH 2RO1 AG15819-06 (David Bennett), “Risk Factors, Pathology, and Clinical Expression of Alzheimer’s disease”, 7/01/98-6/30/08.
Co-Investigator, NIH RO1 AG11101 (Denis A. Evans), “Risk Factors for Incident Alzheimer’s Disease in a Biracial Community” 3/01/93-9/30/09.
Co-investigator, NIH R01 AG17917 (David Bennett) “Epidemiologic Study of Neural Reserve and Neurobiology of Aging” 9/30/01-8/31/06.
Co-Mentor Alzheimer’s Disease Association (Zoe Arvanitakis) “Markers of Oxidative Stress in Mild Cognitive Impairment”, (10/1/04-9/30/06).
Co-Mentor, NIH K23 AG 023675 (Zoe Arvanitakis) “Oxidative Stress, Aging, and Alzheimer’s Disease”, (1/15/05-12/31/09).
Co-Investigator, NIH RO1 ES10902 (Carlos Mendes De Leon) “SES and Age-Related Disability in a Biracial Community”, (8/1/05-7/31/10).
Co-Investigator, NIH, RO1 AG024871 (Robert S. Wilson) “Neurobiologic Study of Psychological Distress and Dementia in Clinical Alzheimer’s Disease”, (7/01/06-6/30/10).
Neurobiologist (subcontract of RADC with Children’s Hospital of Boston), NIH R01 AG027040 (Bruce A. Yankner) “Aging through the Lifespan: Longitudinal Data Analyses”, (12/1/2005-11/30/2009).
Neurobiologist (subcontract of RADC with the University of Kentucky) AG026147 ( Steven Estus) “LDLR, Genetics, Splicing, and AD”, (7/01/06-6/31/10).
Co-Investigator, Rush Translational Sciences Grant, “Circulating Inflammatory Markers and Temporal Lobe Integrity” (Deborah Fleischman, PI, Rush Alzheimer’s Disease Center).
2006- Co-Investigator, Rush Translational Sciences Grant, “Epidemiological Study of Dietary Fats and Metals, Inflammation and Cognition” (Martha Clare Morris, PI, Rush Institute for Healthy Aging).
Co-investigator, NIH RO1 AG030146 “Genetic Epidemiology of Cognitive Decline in an Aging Population Sample” (Denis Evans, Rush Institute for Health Aging, PI).
Co-investigator, competitive supplement to R01 AG22018 “Risk Factors for Cognitive Decline in African Americans” (Lisa Barnes, PhD).
Co-investigator, Alzheimer’s Association, “Stress, Inflammatory Markers and Cognitive Decline in Older Adults” (Lisa Barnes PhD).
Principle Investigator, NIH R21 AG030346-01A2 â€œRelationship between AD Clinicopathological Changes and CNS Sex Steroid Hormones. 9/2008- 8/2010 (A no cost extension of grant was approved at UNM until 8/31/2012).
1) Kelly J.F. and Feigenbaum L.Z.Another Cause of Reversible Dementia: Sleep Deprivation Due to Prostatism, J. Am. Geriatr. Soc. 30: 645-46, l982.
2) Williams R.L., Upton R.A., Cello J.P., Jones R.M., Blitstein M., Kelly J. and Nirenberg, D., Naproxen Disposition in Patients with Laennec’s Cirrhosis, European J. Clin. Pharm. 27: 29l-96, l984.
3) Upton R.A., Williams R.L., Kelly J.F., Jones R.M., Naproxen Pharmacokinetics in the Elderly, Br. J. Clin. Pharm., l8: 207-l4, l984.
4) Kelly J.F. and Winograd C., A Functional Approach to Stroke Management in Elderly Patients, J. Am. Geriatr. Soc., 33: 48-60, l985.
5) Kelly J.F. and Greenblatt D.J., Rapid and Sensitive Gas Chromatographic Determination of Estazolam, J. Chromatography 621:102-104, 1993.
6) Joseph J.A., Algeri S., De’Cesare A., Comuzio M., Erat S. and Kelly J. Caloric Restriction Retards Age-associated Decreases in Muscarinic Receptor Sensitivity, Neurobiol. Aging 16: 607-612, 1995.
7) Kelly J.F., Joseph J.A., Denisova N., Erat S., Mason R.P. and Roth G.S., Dissociation of Striatal GTPase and Dopamine Release Responses to Muscarinic Cholinergic Agonists in F344 Rats.Â Influence of Age and Dietary Manipulation, J. Neurochem. 64: 2755-2764, 1995.
8) Joseph J.A.,Villabolbos-Molina, R.,Yamagami, K. Roth G.S. and Kelly, J.,Â Age-Specific Alterations in Muscarinic Stimulation of K+-Evoked Dopamine Release From Striatal Slices by Cholesterol and S-Adenosyl-L- Methionine,Â Brain Res. 673: 185-193, 1995.
9) Kowatch M.A., Kelly J.F., Denisova N. and Roth G.S, Partial Restoration of Impaired Alpha1 -adrenergic Responsiveness in Parotid Cells of Aged rats by S-Adenosy-L-methionine Treatment, Mol. Cell. Biochem. 148: 73-77, 1995.
10) Kelly J.F., Mason R.P, Denisova N.A., Erat S, Joseph J.A. and Roth G.S., Age-Related Impairment in Striatal Muscarinic Cholinergic Signal Transduction is Associated with Reduced Membrane Bilayer Width, Biochem. Biophys. Res. Commun. 213: 869-874, 1995.
11) Mason R.P, Estermeyer J.D., Kelly J.F. and Mason P.E., Alzheimer’s Disease Amyloid Î²-peptide is Localized in the Membrane Hydrocarbon Core: X-ray Diffraction Analysis, Biochem. Biophys. Res. Commun.222: 78-82, 1996.
12) Kelly J.F. and Roth G.S. Commentary: Membrane Alterations in Aging and AD: Effects on Muscarinic Cholinergic Signal Transduction. Alzheimer’s Disease Review 1: 14-15, 1996.
13) Kelly J.F., Furukawa K., Barger S.W., Rengen M.R., Mark R.J., Blanc E.M., Roth G.S. and Mattson M.P., Amyloid Î²-peptide Disrupts Carbachol-Induced Muscarinic Cholinergic Signal Transduction in Cortical Neurons, Proc. Natl. Acad. Sci. USA. 93: 6753-6758, 1996.
14) Abugo O., Rao P.R., Kelly J.F., Roth G.S. and Rifkind J.M, Effect of Cholesterol in Diet on Capillary Flow of Rat Erythrocytes. Part 1: Geometric and Flow Characteristics, Clin. Hemorheaology and Microcirculation. 17: 437-443, 1997.
15) Rao P.R., Abugo O., Kelly J.F., Roth G.S. and Rifkind J.M., Effect of Cholesterol Content in Diet on Capillary Flow of Rat Erythrocytes. Part ll: Mechanical Properties, Clin. Hemorhealogy and Microcirculation 17: 445-457, 1997.
16) Blanc E.M., Kelly J.F., Mark R.J. and Mattson M.P, 4-Hydroxynonenal, an Aldehydic Product of Lipid Peroxidation, Impairs G Protein Coupling with Muscarinic Acetylcholine and Metabotropic Glutamate Receptors: A Direct Action on Gq/11, J. Neurochem 69: 570-580, 1997.
17) Denisova N.A., Erat S.A., Kelly J.F. and Roth G.S. Differential Effect of Aging on Cholesterol Modulation of Carbachol Stimulated low Km GTPase Activity, Exp. Gerontol. 33: 249-265, 1998.
18) Perichon R., Bourre J.M., Kelly J.F. and Roth G.S. The Role of Peroxisomes in Aging, Cell. Mol. Life Sci.54: 641-652, 1998.
19) Cutler R.G, Kelly J.F., Storie K., Pedersen W.A, Tamara A., Hatanpaa K., TroncosoÂ J.C. and Mattson M.P.Â Involvement of Oxidative Stress-Induced Abnormalities in Ceramide and Cholesterol Metabolism in Brain Aging and Alzheimer’s Disease, Proc.Natl. Acad. Sci. USA 101: 2070-2075, 2004.
20) Kelly J.F., StorieÂ K, Scamra, C, Bienias, J., Beck T., and Bennett DA. Relationship Between Alzheimer’s Disease Clinical Stage and Gq/11 in Subcellular Fractions of Frontal Cortex. J. Neural Transmission 112(8): 1049-1056, 2005.
21) Gopalraj, R.K., Zhu H., Kelly J.F., Pulliam J.F., Bennett D.A., Estus S.Â Genetic Association of Low Density Lipoprotein Receptor and Alzheimer’s Disease, Neurobiol.Â Aging 26: 1-7, 2005.
22) Zhu, H., Gopalraj, R., Kelly, J.F. Bennett, D.A. and Estus, S. Lack Of Genetic Association Of Cholesteryl Ester Transfer Protein Polymorphisms With Late Onset Alzheimer’s Disease. Neurosci. Lett. 381: 36-41, 2005.
23) Lopez, M.F., Mikulskis, A., Kuzdzal, S., Bennett, D.A., Kelly, J.F. et al., High Resolution Serum Proteomic Profiling Of Alzheimer’s Disease Samples Reveals Disease-Specific Carrier Protein-Bound Mass Signatures. Clinical Chemistry 51: 1946-1954, 2005.
24) Boyle, P, A, Wilson, R.S. Aggarwal, N.T., Arvanitakis, Z, Kelly, J., Bienias, J. L, and Bennett, D.A. Parkinsonian Signs in Subjects with Mild Cognitive Impairment. Neurology 65: 1901-1906, 2005.
25) Bennett, D.A., Schneider, J.A., Arvanitakis, Z., Kelly, J.F., Aggarwal, N.T., Shah, R.C.and Wilson, R.S. Neuropathology of Older Persons Without Cognitive Impairment from Two Community-Based Studies. Neurology 66: 1837-1844, 2006.
26) Bennett, D.A.., Schneider, J.S., Aggarwal, N.T., Arvanitakis, Z, Shah, R.C., Kelly, J.F., Fox, J.H., Cochran, E.J., Arends, D.Treinkman, A.D., Wilson, R.S. Decision Rules Guiding the Clinical Diagnosis of Alzheimer’s Disease in Two Community-Based Cohort Studies Compared to Standard Practice in a Clinic-Based Cohort Study. Neuroepidemiology 27; 169-176, 2006.
27) Wilson, R.S., Arnold, S.E., Schneider, J.A., Kelly, J.F., Tang, Y, Bennett, D.A. Chronic Psychological Distress and Risk of Alzheimer’s Disease in Old Age. Neuroepidemiology 27: 143-153, 2006.
28) Schipper, H.M., Bennett, D.A., Liberman, A., Bienias, J., Kelly, J.F., Arvanitakis, Z.Â Glial Heme Oxygenase-1 Expression in Alzheimer’s Disease and Mild Cognitive Impairment. Neurobiol. Aging; 27: 252-261, 2006.
29) Wilson, R.S., Krueger, K.R., Arnold, S.E., Schneider, J.A., Kelly, J.F., Barnes, L.L., Tang, X., and Bennett, D.A. Loneliness and Risk of Alzheimer’s Disease. Arch. Gen. Psych; 64(2):234-40, 2007.
30) Boyle, P.A., Wilson, R.S., Buchman, A.S., Aggarwal, N.T., Tang, Y., Arvanitatkis, Z., Kelly, J. and Bennett, D.A. Lower Extremity Motor Function and Disability and Mild Cognitive Impairment. Exp. Aging Res. 33(2); 355-71, 2007.
31) Kelly J.F., Bienias J.L., Shah, A., Meeke, K.A., Schneider, J.A., Soriano, E. and Bennett, D.A. Levels of Estrogen Receptors Î± and Î² in Frontal Cortex of Patients with Alzheimer’s Disease:Â Relationship to Mini-Mental State Examination Scores. Curr. Alz. Res; 5 (1) : 45-51, 2008.
32) Arvanitakis, Z., Schneider, J.A., Wilson, R.S., Bienias, J.L., Kelly, J.F., Evans, D.A. Bennett, D.A. Statins, Incident AD, Change In Cognitive Function, and Neuropathology. Neurology 70; (19 Pt 2): 1795-802, 2008.
33) Fanggeng Zou, Rangaraj K. Gopalraj, Johann Lok, Haiyan Zhu, I-Fang Ling, James F. Simpson, H. Michael Tucker, Jeremiah F. Kelly, David A. Bennett, Steven G. Younkinand Steven Estus. Sex-dependent Association of a Common Low Density Lipoprotein Receptor Polymorphism with RNA Splicing Efficiency in the Brain and Alzheimers Disease. Human Molecular Genetics. 7: 929-35, 2008.
34) Arvanitakis, Z. Grodstein F, Schneider JA, Wilson RS, Bienias JL, Kelly JF, Evans DA, Bennett DA. The Relation Of NSAIDS To Incident AD, Change In Cognitive Function, And AD Pathology. Neurology. 70: 2219-2232, 2008.
35) Buchman, A., Boyle, P.A., Wilson, R.S., Beck, T., Kelly, J.F., and Bennett, D.A. Apolipoprotein E Îµ4 Allele is Associated with More Rapid Motor Decline in Older Persons. Alz. Dis Assoc Disorders. Alz. Dis. Assoc. Disorders 2009; 23(1):63-69.
36) Rhodes, B,Â Morris, D.L., , Subrahmanyan, L., Aubin,C., Kelly J.F., Evans, D.A. Whittaker, J.C, Mendes de Leon, C.F, Oksenburg, J., de Jager, P.J., Vyse.T . Fine Mapping the Genetic Basis of CRP Regulation in African Americans: A Bayesian Approach. Human Genetics. 123 (6): 633-642, 2008.
37) Boyle, P.A.,Buchman, A.S., Wilson, R.S., Kelly, J.F. and Bennett, D.A. The ApoE Îµ4 Allele Is Associated with Incident Mild Cognitive Impairment Among Community-Dwelling Older Persons. Neuroepidemiology 2010; 34(1): 43-49.
38) Lewis, T.T., Aiello, A., Leurgans, S., Kelly, J and Barnes, L.L. Self-reported Experiences of Discrimination are associated with Elevated C-Reactive Protein levels in Older African-American Adults. Â Brain, Behavior and Immunity. 2010 Mar; 24(3): 438-443.
39) Soetanto,A., Wilson,R.S., Talbot, K., Un, A., Schneider, J.A. Sobiesk, M., Kelly, J., Sue Leurgans, S., Bennett, D.A. and Steven E. Arnold, S.E. Anxiety and Depression Are Associated with MAP2 and Synaptopodin Immunolabeled Dendrite and Spine Densities in Hippocampal CA3 of Older Humans. Arch. Gen. Psych. 2010 May; 67(5): 448-457.
40) Fleischman, D.M., Arfanakis, K., Kelly, J.F., Buchman, A., Morris, M.C… Barnes, L., and Bennett, D.A. Regional Brain Cortical Thinning and Systemic Inflammation in Older Persons Without Dementia. J Am. Geriatr. Soc. 2010 Sept; 58(9): 1823-1825.
41) Barnes, LL, Arvanitakis Z, Lu, L, Kelly J, De Jager PL, Bennett DA. Â Apolipoprotein E and Change in Episodic Memory in Blacks and Whites. Neuroepidemiology 2013 January 24; 40(3) 211-219.
1) Upton R.A., Williams R.L., Kelly J.F., Cello J.P., Altered Disposition of Naproxen by Cirrhotic and by Elderly Individuals. In L.Z. Benet, G. Levy and B.L. Ferrailo (Eds): Pharmacokinetics. A Modern View, Plenum Press, New York, 1984.
2) Kelly J.F., Clinical Pharmacology of Chemotherapeutic Agents in Old Age, Front. Radiat. Ther. Onc. Vol. 20 pp l0l-lll. Karger, Basel, l986.
3) Kelly J.F., Stroke Rehabilitation in Geriatrics. In B. Kemp, K. Brummel-Smith and J Ramsdell (Eds): Geriatric Rehabilitation, College Hill Press, Boston, 1989.
4) Kelly J.F. and Roth G.S., Changes in Neurotransmitter Signal Transduction Pathways in the Aging Brain. In M.P. Mattson and J.W. Geddes, The Aging Brain. Advances in Cell Aging and Gerontology, Vol. 7, JAI Press Inc., Greenwich, CT., 1997
Proceedings and Non-Refereed Papers
1) Kelly J.F., New Developments in the Understanding of Vitamin D and its Metabolites, University of California, San Francisco, Pharmacy and Therapeutics Forum 29:l-3, 1981.
2) Lichtenstein H., Dunn R., Kelly J. and Schwartzbord, S., Geriatric Medicine (letter), Ann Intern Med 96:l2l, l982.
3) Kelly J.F., Vitamin D. Formulations, Q & A Forum, Hospital Formulary, l7:89l-92, l982.
4) Consensus Conference, Differential Diagnosis of Dementing Diseases. JAMA 258:3411-6, 1987.
5) Kelly J.F., Steel K., et al. al., Implementation of Geriatric Medicine Fellowship Guidelines: Suggestions for Program Directors, American Geriatrics Society, 1989.
6) Perichon R., Droy-Lefaix M.T., Kelly J.F., Cunningham S.C., Mason R.P, Roth G.S.Â Effect of Ginko biloba extract (EGb761) on Muscarinic Cholinergic Signal Transduction in Rat Brain Synaptosomes during Aging. L. Packer and Y. Christen (Eds). Advances in Ginko biloba Extract Research (EGb 761), volume 7. Ginko biloba Extract (EGb 761): Lessons from Cell Biology.