Peyronie’s Disease (PD) is an abnormal build up of scar tissue along the shaft of the penis under the skin. It causes curvature of the penis and pain with erections. Symptoms vary and PD may present with penile shortening or impotence. The cause is unknown although there are a number of unproven theories. PD is not a cancer or malignancy.
PD is not contagious or dangerous to the man or his partner. It can have a major impact on sexual functioning and relationships and some men have a lot of distress and anxiety about the condition.
We have a lot of experience in managing this difficult problem. Medical treatments have been aimed at preventing or reducing scar formation. Oral medications that have been used are Vitamin E, colchicine, and Potaba. Recently pentoxyphylline has been felt to impact scar formation and is being used by some thought leaders.
Surgical treatments have been aimed at straightening the penis and sometimes removing the scar tissue as well. Nesbitt operations and occasionally graft placement at the scar site are done. In patients with impotence and PD a penile prosthesis placement is often a great approach. We evaluate each case with a detailed history, assess sexual functioning, and occasionally image the plaques with ultrasound. Treatment options are often patient driven with physician input.